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Shinnosuke Kuroda

Shinnosuke Kuroda

Yokohama City University Medical Center, Japan

Title: Retrograde intrarenal surgery for urinary stone disease in patients with solitary kidney: A retrospective analysis of the efficacy and safety

Biography

Biography: Shinnosuke Kuroda

Abstract

Objectives: To compare outcomes of retrograde intrarenal surgery for urolithiasis between patients with solitary kidneys and patients who have single-side urolithiasis with bilateral kidneys.

Methods: We retrospectively analyzed outcomes of retrograde intrarenal surgery in solitary kidney patients (group A) carried out during 2007-2014 and in patients with bilateral kidneys with comparable stone burdens (group B). Stone-free status was defined as no residual fragment on computed tomography 1 month later.

Results: There were 19 patients in group A (mean age 62.5±18.4 years, range 14-76 years). The mean stone diameter and burden were 6.0 mm (range 3-24 mm) and 10.42±6.92 mm, respectively. The stone-free rate was 94.7% and no repeat procedure was required. The glomerular filtration rate tended to rise post-surgery (postoperative day-1: 48.67±15.92 mL/min, 100.2%, P=0.940; postoperative month-1: 51.32±16.90 mL/min, 105.7%, P=0.101) compared with preoperative rates. The stone-free rate and surgery time were not significantly different between the two groups, although post-surgical hospitalization time was longer for group A (4.05 vs. 3.08 days, P=0.037). The change in glomerular filtration rate was not significantly different between groups A and B (postoperative day-1: +0.101 vs. +0.547 mL/min, respectively, P=0.857; postoperative month-1: +2.749 vs. 3.161 mL/min, respectively, P=0.882). No significant difference was found in terms of complication rate.

Conclusions: Retrograde intrarenal surgery in solitary kidney patients is as safe and effective as in bilateral kidney patients.